Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 10/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938815 | 0.89 | ACE (0.71) | ACEKMT2AFFAR2LMNAALDH1A1 | |
| SCHEMBL11066115 | 0.89 | ACE (0.71) | ACEKMT2AFFAR2LMNAALDH1A1 | |
| SCHEMBL29888703 | 0.89 | ACE (0.73) | ACEKMT2AFFAR2LMNAALDH1A1 | |
| SCHEMBL10979196 | 0.89 | ACE (0.77) | ACEKMT2AFFAR2LMNAALDH1A1 | |
| SCHEMBL10969779 | 0.89 | ACE (0.77) | ACEKMT2AFFAR2LMNAALDH1A1 | |
| SCHEMBL11185062 | 0.89 | ACE (0.77) | ACEKMT2AFFAR2LMNAALDH1A1 | |
| SCHEMBL11096475 | 0.89 | ACE (0.67) | ACEKMT2AFFAR2LMNAALDH1A1 | |
| SCHEMBL10970883 | 0.88 | ACE (0.56) | ACEKMT2AFFAR2 | |
| SCHEMBL10968013 | 0.87 | ACE (0.54) | ACEKMT2AFFAR2LMNAALDH1A1 | |
| SCHEMBL11195371 | 0.87 | ACE (0.73) | ACEKMT2AFFAR2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048763-B1 | SULFUR-CONTAINING ACYLAMINO ACIDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-11-06 | — | — | EP | disclosed |
| US-4425333-A | HYPOTENSIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |
| EP-0048763-A1 | SULFUR-CONTAINING ACYLAMINO ACIDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-04-07 | — | — | EP | disclosed |