Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 12/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066115 | 1.00 | ACE (0.71) | ACEKMT2ALMNAFFAR2HTT | |
| SCHEMBL10941485 | 0.90 | ACE (0.57) | ACEKMT2ALMNAFFAR2HTT | |
| SCHEMBL10968295 | 0.89 | ACE (0.71) | ACEKMT2ALMNAFFAR2HTT | |
| SCHEMBL10979196 | 0.89 | ACE (0.77) | ACEKMT2ALMNAFFAR2HTT | |
| SCHEMBL10969779 | 0.89 | ACE (0.77) | ACEKMT2ALMNAFFAR2HTT | |
| SCHEMBL11185062 | 0.89 | ACE (0.77) | ACEKMT2ALMNAFFAR2HTT | |
| SCHEMBL29888703 | 0.87 | ACE (0.73) | ACEKMT2ALMNAFFAR2HTT | |
| SCHEMBL11195371 | 0.87 | ACE (0.73) | ACEKMT2ALMNAFFAR2HTT | |
| SCHEMBL11061437 | 0.86 | KMT2A (0.58) | ACEKMT2ALMNAFFAR2ALDH1A1 | |
| SCHEMBL11096475 | 0.86 | ACE (0.67) | ACEKMT2ALMNAFFAR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048763-B1 | SULFUR-CONTAINING ACYLAMINO ACIDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-11-06 | — | — | EP | disclosed |
| EP-0067885-B1 | HETEROCYCLIC 5-MEMBERED RING COMPOUNDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-09-04 | — | — | EP | disclosed |
| US-4464371-A | HYPOTENSIVE AGENTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| US-4425333-A | HYPOTENSIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |
| EP-0067885-A1 | HETEROCYCLIC 5-MEMBERED RING COMPOUNDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-12-29 | — | — | EP | disclosed |
| EP-0048763-A1 | SULFUR-CONTAINING ACYLAMINO ACIDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-04-07 | — | — | EP | disclosed |