SCHEMBL10968356

SCHEMBL10968356

Oc1cc2[c]cccc2[nH]1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.30
DDO Q99489 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9853649 0.77 AOC3 (0.30)
SCHEMBL1816734 0.75
SCHEMBL934168 0.75 CYP1A2 (0.41) DAODDO
SCHEMBL9537423 0.75 RHEB (0.37)
SCHEMBL3483057 0.73 KDM4E (0.53) DAO
SCHEMBL9537154 0.72 RHEB (0.37)
SCHEMBL2470257 0.72 RHEB (0.40) DAO
SCHEMBL9202723 0.71 ALDH1A1 (0.47)
SCHEMBL10971264 0.71 KDM4E (0.33)
SCHEMBL9537455 0.71 KDM4E (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0164633-A2 Indole derivatives MERCK PATENT GmbH (DE) 1985-12-18 EP disclosed