Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.67 |
| ▸ | FFAR2 | O15552 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10966449 | 0.88 | ACE (0.50) | ACEFFAR2HTTLMNA | |
| SCHEMBL10966516 | 0.88 | ACE (0.50) | ACEFFAR2HTTLMNA | |
| SCHEMBL11128548 | 0.85 | ACE (0.47) | ACEFFAR2TBXA2R | |
| Rentiapril SCHEMBL11065900 | 0.81 | ACE (1.00) | ACEFFAR2HTTLMNAALDH1A1 | |
| Rentiapril SCHEMBL30422754 | 0.81 | ACE (1.00) | ACEFFAR2HTTLMNAALDH1A1 | |
| Rentiapril SCHEMBL323403 | 0.81 | ACE (1.00) | ACEFFAR2HTTLMNAALDH1A1 | |
| Rentiapril SCHEMBL294980 | 0.81 | ACE (1.00) | ACEFFAR2HTTLMNAALDH1A1 | |
| SCHEMBL10967167 | 0.80 | ACE (0.41) | ACEFFAR2 | |
| SCHEMBL683192 | 0.77 | ACE (0.72) | ACEHTTALDH1A1POLB | |
| SCHEMBL10970454 | 0.77 | ACE (0.69) | ACEFFAR2LMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4425333-A | HYPOTENSIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | claimed |
| EP-0048763-B1 | SULFUR-CONTAINING ACYLAMINO ACIDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-11-06 | — | — | EP | disclosed |
| EP-0048763-A1 | SULFUR-CONTAINING ACYLAMINO ACIDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-04-07 | — | — | EP | disclosed |