Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10966449 | 0.93 | ACE (0.50) | ACEKMT2AFFAR2HTTLMNA | |
| SCHEMBL10968424 | 0.88 | ACE (0.67) | ACEFFAR2HTTLMNA | |
| SCHEMBL11128548 | 0.87 | ACE (0.47) | ACEKMT2AFFAR2 | |
| SCHEMBL11066115 | 0.83 | ACE (0.71) | ACEKMT2AFFAR2HTTLMNA | |
| SCHEMBL10938815 | 0.83 | ACE (0.71) | ACEKMT2AFFAR2HTTLMNA | |
| SCHEMBL10967167 | 0.81 | ACE (0.41) | ACEKMT2AFFAR2 | |
| SCHEMBL10941485 | 0.80 | ACE (0.57) | ACEKMT2AFFAR2HTTLMNA | |
| SCHEMBL10966510 | 0.79 | ACE (0.49) | ACEKMT2ALMNA | |
| SCHEMBL10968295 | 0.76 | ACE (0.71) | ACEKMT2AFFAR2HTTLMNA | |
| SCHEMBL10971131 | 0.75 | ACE (0.48) | ACEKMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4425333-A | HYPOTENSIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | claimed |
| EP-0048763-B1 | SULFUR-CONTAINING ACYLAMINO ACIDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-11-06 | — | — | EP | disclosed |
| US-4425333-A | HYPOTENSIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |
| EP-0048763-A1 | SULFUR-CONTAINING ACYLAMINO ACIDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-04-07 | — | — | EP | disclosed |