SCHEMBL109685

SCHEMBL109685

Nc1ccc(-c2ccc(N)cc2C(F)(F)F)c(C(F)(F)F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 1.00
GAA P10253 2/20 1.00
POLB P06746 2/20 1.00
GLA P06280 1/20 1.00
KIF11 P52732 4/20 0.45
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 3/20 0.43
AR P10275 2/20 0.43
MAPK1 P28482 2/20 0.43
MEN1 O00255 2/20 0.43
HPGD P15428 2/20 0.43
KMT2A Q03164 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
SRC P12931 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
ATM Q13315 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TLR9 Q9NR96 1/20 0.43
NR1H2 P55055 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17451259 1.00 TSHR (1.00) TSHRGAAPOLBGLAKIF11
SCHEMBL29350569 1.00 TSHR (1.00) TSHRGAAPOLBGLAKIF11
Hydrochloric Acid SCHEMBL8642589 0.98 TSHR (0.95) TSHRGAAPOLBGLAKIF11
Water SCHEMBL20506731 0.98 TSHR (0.95) TSHRGAAPOLBGLAKIF11
Ammonia Solution, Strong SCHEMBL6812982 0.98 TSHR (0.95) TSHRGAAPOLBGLAKIF11
SCHEMBL22589784 0.95 TSHR (0.91) TSHRGAAPOLBGLAKIF11
SCHEMBL22606820 0.95 TSHR (0.91) TSHRGAAPOLBGLAKIF11
SCHEMBL22607200 0.95 TSHR (0.91) TSHRGAAPOLBGLAKIF11
SCHEMBL22606813 0.93 TSHR (0.87) TSHRGAAPOLBGLAKIF11
SCHEMBL28986790 0.93 TSHR (0.87) TSHRGAAPOLBGLAKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7350 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257623-B1 PHOTOSENSITIVE POLYIMIDE RESIN COMPOSITION, RESIN FILM, AND ELECTRONIC DEVICE MITSUBISHI GAS CHEMICAL CO (JP) 2026-05-27 EP claimed
US-12637560-B2 Resin composition DUPONT ELECTRONIC MATERIALS INTERNATIONAL, LLC (US) 2026-05-26 US claimed
US-12630739-B2 Polyimide precursor composition and optical multilayer structure formed using the same SK INNOVATION CO., LTD. (KR) 2026-05-19 US claimed
US-12630470-B2 Polyamideimide film and window cover film including the same SK INNOVATION CO., LTD. (KR) 2026-05-19 US claimed
US-20260132262-A1 BLACK POLYIMIDE FILM AND THE MANUFACTURING METHOD THEREOF PI ADVANCED MAT CO LTD (KR) 2026-05-14 US claimed
US-20260132256-A1 POLYAMIC ACID COMPOSITION AND POLYIMIDE PREPARED WITH THE SAME PI ADVANCED MAT CO LTD (KR) 2026-05-14 US claimed
US-20260125577-A1 SELF-LUBRICATING POLYIMIDE VARNISH AND POLYIMIDE COATING PREPARED THEREFROM PI ADVANCED MAT CO LTD (KR) 2026-05-07 US claimed
US-12619010-B2 Optical multilayer structure and method of manufacturing the same SK INNOVATION CO., LTD. (KR) 2026-05-05 US claimed
US-12619005-B2 Optical film with improved optical properties, display apparatus comprising same, and manufacturing method therefor KOLON INDUSTRIES, INC. (KR) 2026-05-05 US claimed
US-20260102993-A1 ELECTRICALLY INSULATING LAMINATES FOR ELECTRIC MACHINE APPLICATIONS DUPONT ELECTRONICS INC (US) 2026-04-16 US claimed
EP-0557985-A1 Preparation of aromatic polyamides from CO, aromatic diamine and di(trifluoro methane sulfonate) EASTMAN CHEMICAL COMPANY (US) 1993-09-01 EP claimed
EP-0557987-A1 Preparation of aromatic poly(imide-amide)s from co, primary diamine and di(trifluoro methane sulfonate)containing phthalimide group EASTMAN KODAK COMPANY (US) 1993-09-01 EP claimed
EP-0557984-A2 Method for the preparation of aromatic polyimides EASTMAN CHEMICAL COMPANY (US) 1993-09-01 EP claimed
US-5216118-A Preparation of aromatic polyimides from CO, primary diamine and bis (halo aromatic carboxylic acid ester) EASTMAN KODAK COMPANY (US) 1993-06-01 US claimed
US-5214123-A Metal-mediated carbonylation and coupling of diamine and phthalimide ring-containing di/trifluoromethanesulfonate/ compound in solvent with platinum, palladium or nickel catalyst EASTMAN KODAK COMPANY (US) 1993-05-25 US claimed
US-5210175-A Catalyst of platinum, palladium or nickel EASTMAN KODAK COMPANY (US) 1993-05-11 US claimed
EP-0527100-A2 Low TCE polyimides as improved insulator in multilayer interconnected structures International Business Machines Corporation (US) 1993-02-10 EP claimed
US-5175242-A PHENYLATED POLYIMIDES PREPARED FROM 3,6-DIARYLPYROMELLITIC DIANHYDRIDE AND AROMATIC DIAMINES THE UNIVERSITY OF AKRON (US) 1992-12-29 US claimed
US-5115090-A Polyamic acids and polyimides for multilayer elements, imsulators and passivation layers INTERNATIONAL BUSINESS MACHINES CORPORATION 1992-05-19 US claimed
EP-0459386-A1 Preparation of polyamides EASTMAN KODAK COMPANY (US) 1991-12-04 EP claimed