Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL6812982

N.N.Nc1ccc(-c2ccc(N)cc2C(F)(F)F)c(C(F)(F)F)c1

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.95
GAA P10253 2/20 0.95
POLB P06746 2/20 0.95
GLA P06280 1/20 0.95
KIF11 P52732 4/20 0.44
ALDH1A1 P00352 3/20 0.42
AR P10275 2/20 0.42
KDM4E B2RXH2 2/20 0.42
MEN1 O00255 2/20 0.42
HPGD P15428 2/20 0.42
KMT2A Q03164 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
SRC P12931 1/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
ATM Q13315 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TLR9 Q9NR96 1/20 0.42
MAPK1 P28482 2/20 0.41
NR1H2 P55055 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL109685 0.98 TSHR (1.00) TSHRGAAPOLBGLAKIF11
SCHEMBL17451259 0.98 TSHR (1.00) TSHRGAAPOLBGLAKIF11
SCHEMBL29350569 0.98 TSHR (1.00) TSHRGAAPOLBGLAKIF11
Hydrochloric Acid SCHEMBL8642589 0.95 TSHR (0.95) TSHRGAAPOLBGLAKIF11
Water SCHEMBL20506731 0.95 TSHR (0.95) TSHRGAAPOLBGLAKIF11
SCHEMBL22607200 0.93 TSHR (0.91) TSHRGAAPOLBGLAKIF11
SCHEMBL22606820 0.93 TSHR (0.91) TSHRGAAPOLBGLAKIF11
SCHEMBL22589784 0.93 TSHR (0.91) TSHRGAAPOLBGLAKIF11
SCHEMBL22606813 0.91 TSHR (0.87) TSHRGAAPOLBGLAKIF11
SCHEMBL28986790 0.91 TSHR (0.87) TSHRGAAPOLBGLAKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2553001-B1 POLYIMIDE POWDER AND FILM KOLON INC (KR) 2019-05-08 EP claimed
EP-3088440-B1 TRANSPARENT POLYAMIDE-IMIDE RESIN AND FILM USING SAME KOLON INC (KR) 2018-09-19 EP claimed
EP-2342266-B1 POLYIMIDE FILM KOLON INC (KR) 2018-08-22 EP claimed
US-9718032-B2 Uncrosslinked, high molecular weight, monoesterified polyimide polymer containing a small amount of bulky diamine CHEVRON U.S.A. INC. (US) 2017-08-01 US disclosed
US-9718033-B2 Uncrosslinked, high molecular weight, polyimide polymer containing a small amount of bulky diamine CHEVRON U.S.A. INC. (US) 2017-08-01 US disclosed
US-20160214067-A1 UNCROSSLINKED, HIGH MOLECULAR WEIGHT, POLYIMIDE POLYMER CONTAINING A SMALL AMOUNT OF BULKY DIAMINE CHEVRON U.S.A. INC. (US) 2016-07-28 US disclosed
US-20160214066-A1 UNCROSSLINKED, HIGH MOLECULAR WEIGHT, MONOESTERIFIED POLYIMIDE POLYMER CONTAINING A SMALL AMOUNT OF BULKY DIAMINE CHEVRON U.S.A. INC. (US) 2016-07-28 US disclosed
US-20040082732-A1 Crosslinkable oligoimides FRANCE TELECOM (FR) 2004-04-29 US disclosed
WO-2000045435-A1 POLYIMIDES USED AS MICROELECTRONIC COATINGS THE UNIVERSITY OF AKRON (US) 2000-08-03 WO disclosed