Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489312 | 0.73 | MAPT (0.34) | LMNAPDK2PDK4MEN1THRB | |
| SCHEMBL27629279 | 0.71 | HCAR2 (0.40) | PDK2PDK4THRBTDP1ALDH1A1 | |
| SCHEMBL2047468 | 0.70 | PDK2 (0.34) | LMNAPDK2PDK4TSHR | |
| SCHEMBL27341400 | 0.68 | HCAR2 (0.30) | — | |
| Ammonia Solution, Strong SCHEMBL7083566 | 0.68 | PDK2 (0.33) | LMNAPDK2PDK4TSHR | |
| SCHEMBL10700103 | 0.68 | PDK2 (0.33) | PDK2PDK4TDP1 | |
| SCHEMBL16360047 | 0.68 | HTR2A (0.35) | PDK2PDK4 | |
| SCHEMBL12962759 | 0.68 | PDK2 (0.33) | PDK2PDK4 | |
| SCHEMBL30065828 | 0.68 | MEN1 (0.39) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28849999 | 0.68 | PDK2 (0.38) | PDK2PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041675-B1 | 4-HALOGEN-5-(TRICHLOROMETHYL-PHENYL)-OXAZOLE DERIVATIVES, PROCESS FOR PREPARING THEM AND RADIATION-SENSITIVE COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-12-11 | — | — | EP | disclosed |
| US-4371607-A | 4-Halogeno-5-(halogenomethyl-phenyl)-oxazole derivatives, a process for the preparation thereof, and radiation-sensitive compositions containing these derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-01 | — | — | US | disclosed |
| EP-0041675-A2 | 4-Halogen-5-(trichloromethyl-phenyl)-oxazole derivatives, process for preparing them and radiation-sensitive compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-12-16 | — | — | EP | disclosed |