SCHEMBL10968802

SCHEMBL10968802

Cc1ccc(-n2nc3ccc4ccccc4c3n2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.72
MAOA P21397 1/20 0.50
SLC2A1 P11166 1/20 0.47
MAPT P10636 8/20 0.46
NPC1 O15118 8/20 0.46
RAB9A P51151 8/20 0.46
KDM4E B2RXH2 7/20 0.46
ALDH1A1 P00352 6/20 0.46
HPGD P15428 4/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
TP53 P04637 4/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
GAA P10253 2/20 0.46
CASP1 P29466 2/20 0.46
HSD17B10 Q99714 2/20 0.46
CASP7 P55210 1/20 0.46
MCL1 Q07820 1/20 0.43
ADORA3 P0DMS8 1/20 0.42
ADORA2A P29274 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23517134 0.92 ALOX5 (0.77) ALOX5MAOASLC2A1MAPTNPC1
SCHEMBL11911493 0.92 ALOX5 (0.62) ALOX5MAOASLC2A1MAPTNPC1
SCHEMBL17155527 0.92 ALOX5 (0.74) ALOX5MAOASLC2A1MAPTNPC1
SCHEMBL14281072 0.87 ALOX5 (0.71) ALOX5MAOASLC2A1MAPTNPC1
SCHEMBL10330358 0.87 ALOX5 (0.70) ALOX5MAOASLC2A1MAPTNPC1
SCHEMBL11911474 0.84 ALOX5 (0.68) ALOX5MAOASLC2A1MAPTNPC1
SCHEMBL12706192 0.84 ALOX5 (0.68) ALOX5MAOASLC2A1MAPTNPC1
SCHEMBL9704256 0.84 ALOX5 (1.00) ALOX5MAOASLC2A1MAPTNPC1
SCHEMBL17155225 0.83 ALOX5 (0.62) ALOX5MAOASLC2A1MAPTNPC1
SCHEMBL14281079 0.83 ALOX5 (0.66) ALOX5MAOASLC2A1MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8080667-B2 Electroluminescent metal complexes with triazoles and benzotriazoles BASF SE (DE) 2011-12-20 US disclosed
US-8080667-B2 Electroluminescent metal complexes with triazoles and benzotriazoles BASF SE (DE) 2011-12-20 US disclosed
US-7820828-B2 Electroluminescent metal complexes with triazoles and benzotriazoles CIBA SPECIALTY CHEMICALS CORP. (US) 2010-10-26 US disclosed
US-7820828-B2 Electroluminescent metal complexes with triazoles and benzotriazoles CIBA SPECIALTY CHEMICALS CORP. (US) 2010-10-26 US disclosed
US-20100244014-A1 ELECTROLUMINESCENT METAL COMPLEXES WITH TRIAZOLES AND BENZOTRIAZOLES UDC IRELAND LIMITED (IE) 2010-09-30 US disclosed
US-20100244014-A1 ELECTROLUMINESCENT METAL COMPLEXES WITH TRIAZOLES AND BENZOTRIAZOLES UDC IRELAND LIMITED (IE) 2010-09-30 US disclosed
US-20080015355-A1 Electroluminescent Metal Complexes With Triazoles And Benzotriazoles UDC IRELAND LIMITED (IE) 2008-01-17 US disclosed
US-20080015355-A1 Electroluminescent Metal Complexes With Triazoles And Benzotriazoles UDC IRELAND LIMITED (IE) 2008-01-17 US disclosed
EP-0031796-B1 4-HETEROCYCLYL-4'-VINYL-STILBENES CIBA-GEIGY AG (CH) 1985-01-23 EP disclosed
US-4366189-A WHITENERS CIBA-GEIGY CORPORATION (US) 1982-12-28 US disclosed
EP-0031796-A2 4-Heterocyclyl-4'-vinyl-stilbenes CIBA-GEIGY AG (CH) 1981-07-08 EP disclosed
US-4276188-A OPTICAL BRIGHTENERS FOR COTTON AND POLYAMIDES CIBA-GEIGY CORPORATION (US) 1981-06-30 US disclosed
US-4167629-A OPTICAL BRIGHTENERS SANDOZ LTD. (CH) 1979-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100244014-A1 ELECTROLUMINESCENT METAL COMPLEXES WITH TRIAZOLES AND BENZOTRIAZOLES OCIAD1, OXA1L, OCIAD2 ALOX5 337/4885MAOA 281/4885SLC2A1 3856/4885
US-20080015355-A1 Electroluminescent Metal Complexes With Triazoles And Benzotriazoles OCIAD1, OXA1L, OCIAD2 ALOX5 313/4885MAOA 320/4885SLC2A1 3523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.