Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 13/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | FAP | Q12884 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10778950 | 0.94 | ACE (0.55) | ACELMNASMN1; SMN2ACE2ALDH1A1 | |
| SCHEMBL10779532 | 0.88 | ACE (0.64) | ACELMNASMN1; SMN2ACE2 | |
| SCHEMBL11207926 | 0.86 | ACE (0.75) | ACELMNASMN1; SMN2CYP3A4 | |
| SCHEMBL10972032 | 0.84 | ACE (0.74) | ACELMNASMN1; SMN2ACE2 | |
| Trifluoroacetic Acid SCHEMBL10971638 | 0.81 | ACE (0.70) | ACELMNASMN1; SMN2ACE2CYP3A4 | |
| SCHEMBL16364868 | 0.81 | ACE (0.85) | ACELMNASMN1; SMN2CYP3A4 | |
| Hydrochloric Acid SCHEMBL10970088 | 0.79 | ACE (0.47) | ACELMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL11209208 | 0.79 | ACE (0.87) | ACELMNASMN1; SMN2CYP3A4 | |
| SCHEMBL11203453 | 0.79 | ACE (0.87) | ACELMNASMN1; SMN2CYP3A4 | |
| SCHEMBL11205558 | 0.79 | ACE (0.87) | ACELMNASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528282-A | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1985-07-09 | — | — | US | disclosed |
| EP-0084941-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-08-03 | — | — | EP | disclosed |