Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10663164 | 0.91 | LMNA (0.36) | — | |
| SCHEMBL10663182 | 0.89 | LMNA (0.34) | ABL1BCR | |
| SCHEMBL10657475 | 0.89 | CDC7 (0.34) | — | |
| SCHEMBL10664690 | 0.89 | — | — | |
| SCHEMBL10659055 | 0.89 | HTR2C (0.36) | — | |
| SCHEMBL10658312 | 0.87 | CDC7 (0.37) | — | |
| SCHEMBL10659843 | 0.85 | LRRK2 (0.42) | — | |
| SCHEMBL10667797 | 0.85 | SLC29A1 (0.40) | — | |
| SCHEMBL10660811 | 0.81 | HTT (0.31) | — | |
| SCHEMBL11030374 | 0.81 | CYP11B1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055444-B1 | TRISUBSTITUTED PYRIMIDO(5,4-D)PYRIMIDINES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1985-03-20 | — | — | EP | disclosed |
| EP-0055444-A2 | Trisubstituted pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1982-07-07 | — | — | EP | disclosed |