Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | DHODH | Q02127 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11098958 | 0.83 | KMT2A (0.38) | KDM4EMAPTCYP2C19MEN1KMT2A | |
| SCHEMBL10971806 | 0.76 | MAPT (0.55) | KDM4EMAPTNPSR1MAPK1L3MBTL1 | |
| SCHEMBL10970247 | 0.75 | MAPT (0.54) | KDM4EMAPTNPSR1MAPK1L3MBTL1 | |
| SCHEMBL10970373 | 0.75 | MAPT (0.54) | KDM4EMAPTNPSR1MAPK1L3MBTL1 | |
| SCHEMBL11610004 | 0.74 | MAPT (0.65) | KDM4EMAPTNPSR1MAPK1L3MBTL1 | |
| SCHEMBL10970489 | 0.74 | MAPT (0.52) | KDM4EMAPTNPSR1MAPK1L3MBTL1 | |
| SCHEMBL10969377 | 0.73 | MAPT (0.51) | KDM4EMAPTNPSR1MAPK1L3MBTL1 | |
| SCHEMBL10967972 | 0.71 | RAB9A (0.59) | KDM4EMAPTNPSR1MAPK1L3MBTL1 | |
| SCHEMBL11608951 | 0.70 | MAPT (0.56) | KDM4EMAPTNPSR1MAPK1L3MBTL1 | |
| SCHEMBL10973850 | 0.70 | MAPT (0.50) | KDM4EMAPTNPSR1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4543356-A | Quinazoline derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-09-24 | — | — | US | disclosed |