SCHEMBL10970537

SCHEMBL10970537

CCOC(C[SiH2]CCCBr)OCC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL702536 0.86 THRB (0.36) THRB
SCHEMBL704452 0.86 THRB (0.36) THRB
SCHEMBL6859233 0.84 THRB (0.35) THRB
SCHEMBL1275414 0.82 CYP1A2 (0.38) THRB
SCHEMBL703186 0.81 THRB (0.40) THRB
SCHEMBL2967471 0.80 THRB (0.32) THRB
SCHEMBL9228655 0.79
SCHEMBL8679112 0.78 THRB (0.31) THRB
SCHEMBL10589332 0.78 MEN1 (0.36) THRB
SCHEMBL4816202 0.77 THRB (0.33) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4524169-A THERMOPLASTIC RUBBER, SILICATE FILLER, AND AN ORGANOSILICON COMPOUND DEGUSSA AKTIENGESELLSCHAFT (DE) 1985-06-18 US disclosed