Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10970533 | 0.91 | KMT2A (0.81) | KMT2AKDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL9616229 | 0.88 | KMT2A (0.79) | KMT2AKDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL10971571 | 0.88 | KMT2A (0.75) | KMT2AKDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL10975334 | 0.88 | KMT2A (0.75) | KMT2AKDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL10970151 | 0.87 | KMT2A (0.57) | KMT2AKDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL10970090 | 0.86 | KMT2A (0.70) | KMT2AKDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL10971030 | 0.86 | KMT2A (0.75) | KMT2AKDM4EMEN1CYP1A2CYP2C19 | |
| Diflufenican SCHEMBL22023 | 0.86 | KMT2A (1.00) | KMT2AKDM4EMEN1CYP1A2CYP2C19 | |
| Diflufenican SCHEMBL8536896 | 0.86 | KMT2A (1.00) | KMT2AKDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL6351378 | 0.86 | KMT2A (0.72) | KMT2AKDM4EMEN1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053011-B1 | NEW HERBICIDAL NICOTINAMIDE DERIVATIVES | MAY & BAKER LIMITED (GB) | 1985-04-03 | — | — | EP | disclosed |
| EP-0053011-A1 | New herbicidal nicotinamide derivatives | MAY & BAKER LIMITED (GB) | 1982-06-02 | — | — | EP | disclosed |