Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6721254 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL10720396 | 0.76 | CYP3A4 (0.46) | KDM4EALDH1A1CYP1A2CYP2C9POLB | |
| SCHEMBL10975754 | 0.75 | ALDH1A1 (0.40) | KDM4EALDH1A1CYP1A2CYP2C9POLB | |
| SCHEMBL7238854 | 0.74 | MAPT (0.40) | KDM4EALDH1A1CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL6371313 | 0.72 | ALDH1A1 (0.44) | KDM4EALDH1A1CYP1A2CYP2C9MEN1 | |
| SCHEMBL29470093 | 0.72 | KDM4E (0.54) | KDM4EALDH1A1CYP1A2CYP2C9POLB | |
| SCHEMBL14416566 | 0.71 | ALDH1A1 (0.56) | KDM4EALDH1A1CYP1A2CYP2C9POLB | |
| SCHEMBL12924994 | 0.71 | KDM4E (0.45) | KDM4EALDH1A1MAPT | |
| SCHEMBL2031055 | 0.70 | ALDH1A1 (0.55) | KDM4EALDH1A1CYP1A2CYP2C9POLB | |
| SCHEMBL6799442 | 0.70 | KDM4E (0.53) | KDM4EALDH1A1CYP1A2CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4491584-A | ANTIARRHYTHMIA AGENTS | RIKER LABORATORIES (US) | 1985-01-01 | — | — | US | disclosed |
| US-4154941-A | ANTIARRHYTHMIC AGENTS | RIKER LABORATORIES, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4071524-A | Derivatives of urea | RIKER LABORATORIES, INC. (US) | 1978-01-31 | — | — | US | disclosed |