Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.42 |
| ▸ | YAP1 | P46937 | 2/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10971210 | 0.90 | ACE (0.51) | ACELMNASMN1; SMN2ACE2KLK5 | |
| SCHEMBL10610279 | 0.84 | ACE (0.60) | ACELMNASMN1; SMN2ACE2 | |
| Hydrochloric Acid SCHEMBL10974449 | 0.84 | ACE (0.62) | ACELMNASMN1; SMN2ACE2 | |
| SCHEMBL10783023 | 0.84 | ACE (0.42) | ACELMNASMN1; SMN2ACE2KLK5 | |
| Hydrochloric Acid SCHEMBL10611825 | 0.84 | ACE (0.59) | ACELMNASMN1; SMN2ACE2 | |
| SCHEMBL10968745 | 0.82 | ACE (0.58) | ACELMNASMN1; SMN2ACE2FKBP1A | |
| Fumaric Acid SCHEMBL10612018 | 0.81 | SMN1; SMN2 (0.62) | ACELMNASMN1; SMN2ACE2 | |
| Maleic Acid SCHEMBL10612014 | 0.81 | SMN1; SMN2 (0.62) | ACELMNASMN1; SMN2ACE2 | |
| SCHEMBL10071093 | 0.81 | ACE (0.64) | ACEKLK7ACE2YAP1KLK5 | |
| SCHEMBL5015695 | 0.80 | ACE (0.70) | ACELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528282-A | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1985-07-09 | — | — | US | disclosed |
| EP-0084941-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-08-03 | — | — | EP | disclosed |