Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.64 |
| ▸ | YAP1 | P46937 | 3/20 | 0.50 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | GYS1 | P13807 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15223627 | 0.91 | KLK5 (0.55) | ACEKLK7KLK5ACE2 | |
| SCHEMBL10071087 | 0.85 | ACE (0.51) | ACEKLK5ACE2PRSS1TMPRSS15 | |
| SCHEMBL10071091 | 0.83 | ACE (0.57) | ACEYAP1KLK7KLK5SPHK1 | |
| SCHEMBL15222270 | 0.81 | KLK5 (0.53) | ACEKLK7KLK5 | |
| SCHEMBL10972707 | 0.81 | ACE (0.55) | ACEYAP1KLK7KLK5ACE2 | |
| SCHEMBL8366819 | 0.80 | DPP4 (0.58) | ACEKLK5PRSS1 | |
| SCHEMBL7321073 | 0.80 | DPP4 (0.58) | ACEKLK5PRSS1 | |
| SCHEMBL10083011 | 0.79 | ACE (0.61) | ACEYAP1KLK5ACE2PRSS1 | |
| SCHEMBL15223617 | 0.79 | ACE (0.58) | ACEKLK5ACE2 | |
| SCHEMBL15828140 | 0.79 | ACE (0.58) | ACEKLK5ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120045393-A1 | LHRH-II PEPTIDE ANALOGS | BRACCO IMAGING SPA (IT) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120045393-A1 | LHRH-II PEPTIDE ANALOGS | LHCGR, GNRHR, FSHR | ACE 2838/4885YAP1 4053/4885KLK7 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.