Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976834 | 1.00 | TDP1 (0.64) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL294606 | 0.94 | TDP1 (0.67) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10971890 | 0.89 | TDP1 (0.64) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10971457 | 0.89 | TDP1 (0.64) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11237046 | 0.88 | TDP1 (0.60) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL5327652 | 0.88 | TDP1 (0.60) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10973029 | 0.86 | TDP1 (0.58) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL2127178 | 0.85 | TDP1 (0.67) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10975825 | 0.85 | TDP1 (0.57) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL21820776 | 0.84 | TDP1 (0.74) | TDP1LMNAADRA2ACNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4390547-A | 2,2-Dimethyl-3-(substituted ethyl)cyclopropane carboxylate pesticidal compositions and methods | KURARAY CO., LTD. (JP) | 1983-06-28 | — | — | US | claimed |
| JP-55011576-A | — | — | None | — | — | JP | disclosed |
| US-4532258-A | Controlling insects, mites, pests | KURARAY CO., LTD. (JP) | 1985-07-30 | — | — | US | disclosed |
| US-4390547-A | 2,2-Dimethyl-3-(substituted ethyl)cyclopropane carboxylate pesticidal compositions and methods | KURARAY CO., LTD. (JP) | 1983-06-28 | — | — | US | disclosed |
| US-4299839-A | Novel pesticides and pesticidal compositions cyclopropanecarboxylates and pesticidal method | KURARAY CO., LTD. (JP) | 1981-11-10 | — | — | US | disclosed |
| JP-S5511576-A | SUBSTITUTED CYCLOPROPANECARBOXYLIC ESTER AND INSECTICIDE CONTAINING THE SAME AS EFFECTIVE COMPONENT | KURARAY CO LTD | 1980-01-26 | — | — | JP | disclosed |