Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642977 | 1.00 | — | — | |
| SCHEMBL4012332 | 0.89 | ALDH1A1 (0.42) | ALDH1A1KMT2AHSD17B10MEN1KDM4E | |
| SCHEMBL423972 | 0.88 | — | — | |
| SCHEMBL11406639 | 0.88 | — | — | |
| SCHEMBL15432296 | 0.87 | MEN1 (0.41) | ALDH1A1KMT2AHSD17B10MEN1KDM4E | |
| SCHEMBL6042558 | 0.87 | CYP1A2 (0.54) | ALDH1A1KMT2AHSD17B10MEN1KDM4E | |
| SCHEMBL799201 | 0.87 | TDP1 (0.54) | KMT2ATDP1GAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL19053073 | 0.87 | KMT2A (0.41) | ALDH1A1KMT2AHSD17B10MEN1KDM4E | |
| SCHEMBL9040661 | 0.85 | ATM (0.56) | ALDH1A1KMT2AMEN1HPGDTDP1 | |
| SCHEMBL429744 | 0.85 | ATM (0.56) | ALDH1A1KMT2AMEN1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4529792-A | Reacting diamine with lactic or glycolic acid; then bischloroformate | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-07-16 | — | — | US | disclosed |
| EP-0030822-B1 | SYNTHETIC ABSORBABLE SURGICAL DEVICES OF POLYESTER AMIDES AND PROCESS FOR MAKING THEM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-09-14 | — | — | EP | disclosed |
| US-4343931-A | FILAMENTS, SUTURES, PROSTHETICS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-08-10 | — | — | US | disclosed |
| EP-0030822-A2 | Synthetic absorbable surgical devices of polyester amides and process for making them | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1981-06-24 | — | — | EP | disclosed |
| US-4205077-A | Benzimidazole sulphides as anthelmintic agents | CIBA-GEIGY CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |
| US-4197307-A | 2-Alkylthio-, 2-alkylsulphinyl- and 2-alkylsulfonyl-6-phenylbenzimidazoles as anthelmintic agents | CIBA-GEIGY CORPORATION (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153723-A | ANILINOMETHYLENEMALONONITRILES | CIBA-GEIGY CORPORATION (US) | 1979-05-08 | — | — | US | disclosed |
| US-4151298-A | ANILINOMETHYLENEMALONONITRILE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1979-04-24 | — | — | US | disclosed |
| US-3987181-A | CERTAIN 2-TRIFLUOROMETHYLBENZIMIDAZOLES AS ANTHELMINTICS | CIBA-GEIGY CORPORATION (US) | 1976-10-19 | — | — | US | disclosed |