⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10256 | 1.00 | — | — | |
| SCHEMBL38654528 | 0.94 | — | — | |
| Fluoride SCHEMBL28130527 | 0.94 | — | — | |
| Benzene SCHEMBL28106203 | 0.82 | NR1H2 (0.31) | — | |
| SCHEMBL460250 | 0.80 | — | — | |
| SCHEMBL8339228 | 0.75 | — | — | |
| SCHEMBL27705479 | 0.75 | — | — | |
| SCHEMBL138136 | 0.75 | PGK1 (0.30) | — | |
| SCHEMBL17115852 | 0.75 | — | — | |
| SCHEMBL891648 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4491584-A | ANTIARRHYTHMIA AGENTS | RIKER LABORATORIES (US) | 1985-01-01 | — | — | US | disclosed |
| US-4154941-A | ANTIARRHYTHMIC AGENTS | RIKER LABORATORIES, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4097481-A | ANTIARRHYTHMIC AGENTS | RIKER LABORATORIES, INC. (US) | 1978-06-27 | — | — | US | disclosed |
| US-4071524-A | Derivatives of urea | RIKER LABORATORIES, INC. (US) | 1978-01-31 | — | — | US | disclosed |
| US-4013670-A | ANTIARRHYTHMICS | RIKER LABORATORIES, INC. (US) | 1977-03-22 | — | — | US | disclosed |
| US-4005209-A | Antiarrhythmic method utilizing fluoroalkoxy-N-piperidyl and pyridyl benzamides | RIKER LABORATORIES, INC. (US) | 1977-01-25 | — | — | US | disclosed |