Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532104 | 0.81 | KDM4E (0.65) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| 2-(2'-Methoxyphenyl)-1H-Indole SCHEMBL31053096 | 0.79 | KDM4E (1.00) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| 2-(2'-Methoxyphenyl)-1H-Indole SCHEMBL5634916 | 0.79 | KDM4E (1.00) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| SCHEMBL10641631 | 0.73 | NPC1 (0.55) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| SCHEMBL10973376 | 0.71 | KDM4E (0.46) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| SCHEMBL29429633 | 0.71 | CA1 (0.71) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| SCHEMBL301996 | 0.71 | CA1 (0.71) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| SCHEMBL29788337 | 0.71 | CA1 (0.71) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| SCHEMBL4553365 | 0.70 | MAPT (0.50) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| SCHEMBL9611885 | 0.69 | GPR84 (0.55) | ALDH1A1MAPTKDM4EHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066993-B1 | QUINOLINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-01-30 | — | — | EP | disclosed |
| US-4435405-A | 2-(AMINOALKYLTHIO) SUBSTITUTED | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-03-06 | — | — | US | disclosed |
| EP-0066993-A1 | Quinoline derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-15 | — | — | EP | disclosed |