Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 9/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1106542 | 0.88 | HPGD (0.38) | HPGDALDH1A1KDM4EF10MAPT | |
| SCHEMBL1096434 | 0.86 | HPGD (0.40) | HPGDALDH1A1KDM4EF10MAPT | |
| SCHEMBL1096102 | 0.85 | HPGD (0.39) | HPGDALDH1A1KDM4EF10MAPT | |
| SCHEMBL1096402 | 0.81 | KDM4E (0.43) | HPGDKDM4EF10MAPTMAPK1 | |
| SCHEMBL1100907 | 0.81 | ITGB1 (0.41) | HPGDALDH1A1KDM4EF10MAPT | |
| SCHEMBL1095197 | 0.81 | KDM4E (0.46) | HPGDKDM4EF10MAPTMAPK1 | |
| SCHEMBL1097081 | 0.80 | KDM4E (0.40) | HPGDKDM4EF10MAPK1POLB | |
| SCHEMBL1095731 | 0.80 | MAPK1 (0.41) | HPGDKDM4EF10MAPK1POLB | |
| SCHEMBL1097154 | 0.79 | F10 (0.37) | HPGDF10MAPTMAPK1 | |
| SCHEMBL1097454 | 0.79 | RAB9A (0.34) | HPGDALDH1A1KDM4EF10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153670-B2 | Factor Xa inhibitors | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-04-10 | — | — | US | claimed |
| US-8153670-B2 | Factor Xa inhibitors | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-04-10 | — | — | US | disclosed |