SCHEMBL10973809

SCHEMBL10973809

CCCCCC(=O)Oc1ccc2nc(S(N)(=O)=O)sc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA2 P00918 20/20 1.00
CA1 P00915 6/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7934088 0.99 CA2 (1.00) CA2CA1
SCHEMBL7933389 0.99 CA2 (1.00) CA2CA1
SCHEMBL7931549 0.92 CA2 (1.00) CA2CA1
SCHEMBL7937535 0.91 CA2 (0.85) CA2CA1
SCHEMBL7935101 0.90 CA2 (0.84) CA2CA1
SCHEMBL10913252 0.90 CA2 (0.84) CA2CA1
SCHEMBL10973390 0.90 CA2 (0.86) CA2CA1
SCHEMBL7931552 0.89 CA2 (0.80) CA2CA1
SCHEMBL7924856 0.87 CA2 (0.82) CA2CA1
SCHEMBL10973392 0.85 CA2 (0.79) CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0070239-B1 BENZOTHIAZOLESULFONAMIDE DERIVATIVES, THEIR PREPARATION AND OPHTHALMIC COMPOSITIONS CONTAINING SAID DERIVATIVES MERCK & CO. INC. (US) 1985-06-05 EP disclosed
US-4416890-A GLAUCOMA TREATMENT MERCK & CO., INC. (US) 1983-11-22 US disclosed
EP-0070239-A1 Benzothiazolesulfonamide derivatives, their preparation and ophthalmic compositions containing said derivatives MERCK & CO. INC. (US) 1983-01-19 EP disclosed