Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MYOF | Q9NZM1 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13239884 | 0.90 | PTGS1 (0.56) | PTGS2PTGS1L3MBTL1MALT1CYP3A4 | |
| SCHEMBL10977699 | 0.85 | PTGS2 (0.64) | PTGS2PTGS1L3MBTL1MALT1LMNA | |
| SCHEMBL10973892 | 0.82 | PTGS2 (0.59) | PTGS2PTGS1L3MBTL1MALT1LMNA | |
| SCHEMBL13239881 | 0.81 | PTGS1 (0.47) | PTGS2PTGS1LMNACYP3A4CYP2C9 | |
| SCHEMBL10978842 | 0.81 | PTGS2 (0.58) | PTGS2PTGS1L3MBTL1MALT1LMNA | |
| SCHEMBL13239896 | 0.80 | PTGS1 (0.46) | PTGS2PTGS1L3MBTL1MALT1LMNA | |
| SCHEMBL1193845 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1L3MBTL1MALT1LMNA | |
| SCHEMBL6132166 | 0.77 | PTGS2 (0.69) | PTGS2PTGS1L3MBTL1MALT1LMNA | |
| SCHEMBL3983431 | 0.77 | PTGS2 (0.69) | PTGS2PTGS1L3MBTL1LMNA | |
| SCHEMBL4028727 | 0.77 | PTGS2 (0.69) | PTGS2PTGS1L3MBTL1MALT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162217-A1 | 1,2,4-Triazacycloalcadiene derivatives | CIBA-GEIGY AG (CH) | 1985-11-27 | — | — | EP | disclosed |