Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGFR | P43088 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10974182 | 1.00 | PDE4D (0.47) | PDE4DALDH1A1KDM4EHKDC1TDP1 | |
| SCHEMBL10954595 | 0.92 | ALDH1A1 (0.54) | PDE4DALDH1A1KDM4EHKDC1TDP1 | |
| SCHEMBL10424947 | 0.92 | PTGER2 (0.41) | PDE4DALDH1A1KDM4EHKDC1TDP1 | |
| SCHEMBL10426182 | 0.92 | PTGER2 (0.41) | PDE4DALDH1A1KDM4EHKDC1TDP1 | |
| SCHEMBL11378893 | 0.92 | PDE4D (0.46) | PDE4DALDH1A1KDM4EHKDC1TDP1 | |
| SCHEMBL11158514 | 0.91 | PDE4D (0.49) | PDE4DALDH1A1KDM4EHKDC1TDP1 | |
| SCHEMBL11160487 | 0.91 | PDE4D (0.49) | PDE4DALDH1A1KDM4EHKDC1TDP1 | |
| SCHEMBL11762189 | 0.90 | PDE4D (0.39) | PDE4DALDH1A1KDM4EHKDC1TDP1 | |
| SCHEMBL9482414 | 0.90 | PDE4D (0.41) | PDE4DALDH1A1KDM4EHKDC1TDP1 | |
| SCHEMBL9482417 | 0.90 | PDE4D (0.41) | PDE4DALDH1A1KDM4EHKDC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4560786-A | Δ8,9 -Prostaglandin derivatives, their preparation and use as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-12-24 | — | — | US | disclosed |