SCHEMBL10974682

SCHEMBL10974682

C=C(C)/C=C/OC(=O)CC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.32
HSD17B10 Q99714 1/20 0.32
ALDH1A1 P00352 4/20 0.32
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10974684 1.00 TDP1 (0.32) TDP1HSD17B10ALDH1A1TSHR
SCHEMBL3503821 0.83 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL9050334 0.83 ALDH1A1 (0.41) TDP1HSD17B10ALDH1A1
SCHEMBL29171113 0.83
SCHEMBL7068625 0.81 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL3503333 0.79 TSHR (0.46) ALDH1A1TSHR
SCHEMBL4865125 0.77
SCHEMBL1783345 0.77
Hydrogen Peroxide SCHEMBL27141842 0.75 ALDH1A1 (0.36) TDP1HSD17B10ALDH1A1TSHR
SCHEMBL11819522 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0089576-B1 1,1-DIACYLOXY-3-ALKYL-4-HYDROXY-2 BUTENES, THEIR PREPARATION AND USE BASF Aktiengesellschaft (DE) 1985-07-10 EP disclosed
EP-0089576-A2 1,1-Diacyloxy-3-alkyl-4-hydroxy-2 butenes, their preparation and use BASF Aktiengesellschaft (DE) 1983-09-28 EP disclosed