⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24017127 | 0.93 | SIGMAR1 (0.43) | — | |
| SCHEMBL15726798 | 0.93 | SIGMAR1 (0.43) | — | |
| SCHEMBL6222621 | 0.93 | HRH3 (0.46) | — | |
| SCHEMBL27382640 | 0.93 | HRH3 (0.46) | — | |
| SCHEMBL11163006 | 0.87 | SIGMAR1 (0.47) | — | |
| SCHEMBL239626 | 0.86 | — | — | |
| SCHEMBL85855 | 0.86 | — | — | |
| SCHEMBL81766 | 0.86 | — | — | |
| SCHEMBL27727014 | 0.85 | SIGMAR1 (0.50) | — | |
| SCHEMBL24017112 | 0.85 | SIGMAR1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562955-B1 | QUINAZOLINE DERIVATIVES AS SRC TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-02-27 | — | — | EP | claimed |
| EP-1218353-B1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2007-10-17 | — | — | EP | claimed |
| US-20060122199-A1 | Quinazoline derivatives as src tyrosine kinase inhibitors | ASTRAZENECA AB (SE) | 2006-06-08 | — | — | US | claimed |
| EP-1562955-A1 | QUINAZOLINE DERIVATIVES AS SRC TYROSINE KINASE INHIBITORS | Astrazeneca AB (SE) | 2005-08-17 | — | — | EP | claimed |
| US-6846827-B1 | Pyrimidine derivatives | ASTRAZENECA AB (SE) | 2005-01-25 | — | — | US | claimed |
| EP-1226126-B1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-01-05 | — | — | EP | claimed |
| CN-1530171-A | Method for asymmetric hydrogenation of carboxylic ester | ˹���ػ�ѧ��Ʒ�ɷ�����˾ | 2004-09-22 | — | — | CN | claimed |
| WO-2004041829-A1 | QUINAZOLINE DERIVATIVES AS SRC TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-05-21 | — | — | WO | claimed |
| EP-1226126-A1 | PYRIMIDINE DERIVATIVES | AstraZeneca AB (SE) | 2002-07-31 | — | — | EP | claimed |
| CN-1088081-C | High solids epoxy coatings based on primary-tertiary diamines | AIR PROD & CHEM (US) | 2002-07-24 | — | — | CN | claimed |
| WO-2001027089-A1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-04-19 | — | — | WO | claimed |
| CN-1151427-A | High solids epoxy coatings based on primary-tertiary diamines | AIR PROD & CHEM (US) | 1997-06-11 | — | — | CN | claimed |
| US-20220153139-A1 | SYSTEM AND METHOD FOR EXTENDING A RANGE OF AN ELECTRIC VEHICLE | LOG 9 MATERIALS SCIENT PRIVATE LIMITED (IN) | 2022-05-19 | — | — | US | disclosed |
| CN-103492404-B | C-4' substituted macrolide derivatives | 大正制药株式会社 | 2016-09-07 | — | — | CN | disclosed |
| CN-105026441-A | Tertiary-nitrogen-atom-containing lactone polymer having polymerizable group, and method for producing same | DAICEL CORP | 2015-11-04 | — | — | CN | disclosed |
| CN-104945311-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBVIE INC | 2015-09-30 | — | — | CN | disclosed |
| CN-1025027-C | Organic compounds and their use as pharmaceuticals | LILLY SA (ES) | 1994-06-15 | — | — | CN | disclosed |
| CN-1005337-B | PREPARATION OF NOVEL PLATINUM COMPLEXES | 中外制药株式会社 | 1989-10-04 | — | — | CN | disclosed |
| CN-1030916-A | Organic compound and as the application of medicine | LILLY SA (ES) | 1989-02-08 | — | — | CN | disclosed |
| CN-85107559-A | The preparation of novel platinum complex | — | 1986-06-10 | — | — | CN | disclosed |