Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18923179 | 0.91 | — | — | |
| SCHEMBL28653199 | 0.91 | — | — | |
| SCHEMBL5408873 | 0.91 | — | — | |
| SCHEMBL15211724 | 0.85 | TSHR (0.46) | LMNASPHK1MAPTTSHRGPR84 | |
| SCHEMBL366647 | 0.85 | TSHR (0.46) | LMNASPHK1MAPTTSHRGPR84 | |
| SCHEMBL24044418 | 0.85 | TSHR (0.46) | LMNASPHK1MAPTTSHRGPR84 | |
| SCHEMBL985792 | 0.85 | TSHR (0.46) | LMNASPHK1MAPTTSHRGPR84 | |
| SCHEMBL12844942 | 0.85 | TSHR (0.46) | LMNASPHK1MAPTTSHRGPR84 | |
| SCHEMBL13601912 | 0.85 | TSHR (0.46) | LMNASPHK1MAPTTSHRGPR84 | |
| SCHEMBL4745188 | 0.85 | TSHR (0.46) | LMNASPHK1MAPTTSHRGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063944-A1 | Polyhydric alcohols | HENKEL CORPORATION (a Delaware corp.) (US) | 1982-11-03 | — | — | EP | claimed |
| EP-0063944-B1 | POLYHYDRIC ALCOHOLS | HENKEL CORPORATION (a Delaware corp.) (US) | 1985-07-10 | — | — | EP | disclosed |
| EP-0054430-B1 | TERTIARY AMINO POLYOLS | HENKEL CORPORATION (a Delaware corp.) (US) | 1985-03-13 | — | — | EP | disclosed |
| EP-0063944-A1 | Polyhydric alcohols | HENKEL CORPORATION (a Delaware corp.) (US) | 1982-11-03 | — | — | EP | disclosed |
| EP-0054430-A1 | Tertiary amino polyols | HENKEL CORPORATION (a Delaware corp.) (US) | 1982-06-23 | — | — | EP | disclosed |
| US-4328371-A | USEFUL IN THE PRODUCTION OF POLYURETHANES | HENKEL CORPORATION (US) | 1982-05-04 | — | — | US | disclosed |