⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28653199 | 1.00 | — | — | |
| SCHEMBL18923179 | 1.00 | — | — | |
| SCHEMBL10975596 | 0.91 | LMNA (0.54) | — | |
| SCHEMBL8956889 | 0.87 | — | — | |
| SCHEMBL3804825 | 0.87 | — | — | |
| SCHEMBL3677002 | 0.84 | TSHR (0.50) | — | |
| SCHEMBL3671291 | 0.79 | — | — | |
| SCHEMBL9228631 | 0.79 | — | — | |
| SCHEMBL10155552 | 0.79 | TSHR (0.46) | — | |
| SCHEMBL3673710 | 0.79 | TSHR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260910-B1 | 3,6-DIPHENYLPYRIDAZINES | Chisso Corporation (JP) | 1992-05-27 | — | — | EP | claimed |
| CN-103214483-B | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors | INCYTE CORP | 2014-12-17 | — | — | CN | disclosed |
| CN-103254190-A | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors | INCYTE CORP | 2013-08-21 | — | — | CN | disclosed |
| CN-103214483-A | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors | INCYTE CORP | 2013-07-24 | — | — | CN | disclosed |
| CN-103214484-A | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors | INCYTE CORP A DELAWARE CORP | 2013-07-24 | — | — | CN | disclosed |
| CN-101448826-A | Heteroaryl substituted pyrrolo [2 ] as janus kinase inhibitors | INCYTE CORP (US) | 2009-06-03 | — | — | CN | disclosed |
| US-7199147-B2 | Rho kinase inhibitors | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-03 | — | — | US | disclosed |
| US-20040138286-A1 | Rho kinase inhibitors | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1403255-A1 | Rho KINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-5637255-A | OPTICALLY ACTIVE FORM, USED FOR OPTICAL OR ELECTROOPTICAL DISPLYING; HIGH TWISTING; DOPANT | ROLIC AG (CH) | 1997-06-10 | — | — | US | disclosed |
| EP-0441213-A2 | Chiral dioxolanes | F. HOFFMANN-LA ROCHE AG (CH) | 1991-08-14 | — | — | EP | disclosed |
| US-5032312-A | Liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0410233-A2 | (4-Arylbutyl) cyclohexane derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-30 | — | — | EP | disclosed |
| EP-0393501-A1 | Liquid crystal components with a trans-3-cyclohexylallyloxy group | F. HOFFMANN-LA ROCHE AG (CH) | 1990-10-24 | — | — | EP | disclosed |
| US-4818430-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1989-04-04 | — | — | US | disclosed |
| EP-0260910-A1 | 3,6-Diphenylpyridazines | Chisso Corporation (JP) | 1988-03-23 | — | — | EP | disclosed |
| US-4626560-A | Novel binding agent compositions, foundry sand compositions and ureido functional organosilicon compounds | UNION CARBIDE CORPORATION (US) | 1986-12-02 | — | — | US | disclosed |
| EP-0077036-B1 | BINDING AGENT COMPOSITIONS | UNION CARBIDE CORPORATION (US) | 1986-01-08 | — | — | EP | disclosed |
| EP-0077036-A1 | Binding agent compositions | UNION CARBIDE CORPORATION (US) | 1983-04-20 | — | — | EP | disclosed |
| US-4046794-A | ANCHORING AGENTS ON GLASS | UNION CARBIDE CORPORATION (US) | 1977-09-06 | — | — | US | disclosed |