Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 14/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11756097 | 0.94 | POLB (0.72) | F2RALDH1A1MAPTHPGDMTNR1B | |
| SCHEMBL10294683 | 0.91 | F2R (0.64) | F2RALDH1A1MAPTHPGDMTNR1B | |
| SCHEMBL10294102 | 0.90 | F2R (0.62) | F2RALDH1A1MAPTHPGDMTNR1B | |
| SCHEMBL2885788 | 0.89 | NLRP3 (0.64) | F2RALDH1A1MAPTHPGDMTNR1B | |
| SCHEMBL13994594 | 0.89 | HDAC3 (0.69) | F2RALDH1A1MAPTHPGDPOLB | |
| SCHEMBL5541810 | 0.89 | F2R (0.61) | F2RALDH1A1MAPTHPGDMTNR1B | |
| SCHEMBL10969527 | 0.89 | KDM4E (0.72) | F2RALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL11749871 | 0.88 | F2R (0.62) | F2RALDH1A1MAPTHPGDMTNR1B | |
| SCHEMBL24538415 | 0.88 | MAPT (0.75) | F2RALDH1A1MAPTHPGDMTNR1B | |
| SCHEMBL8088822 | 0.88 | MEN1 (0.72) | F2RALDH1A1MAPTHPGDMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111844-B1 | PROCESS FOR THE PREPARATION OF 3-ACYLAMINOANILINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-11-27 | — | — | EP | disclosed |
| US-4552699-A | Process for the preparation of 3-acylaminoanilines | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-11-12 | — | — | US | disclosed |
| EP-0111844-A1 | Process for the preparation of 3-acylaminoanilines | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-06-27 | — | — | EP | disclosed |