Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10977617 | 0.90 | CNR1 (0.46) | CNR1CNR2PIK3CDKMT2ANPC1 | |
| SCHEMBL11080762 | 0.85 | CNR1 (0.67) | CNR1CNR2PIK3CDKMT2AMAPT | |
| SCHEMBL10974453 | 0.77 | CNR1 (0.69) | CNR1CNR2PIK3CDKMT2AMAPT | |
| SCHEMBL11075891 | 0.76 | CNR1 (0.65) | CNR1CNR2PIK3CDKMT2AMAPT | |
| SCHEMBL10974218 | 0.75 | CNR1 (0.66) | CNR1CNR2PIK3CDKMT2AMAPT | |
| SCHEMBL10980285 | 0.73 | PIK3CD (0.56) | PIK3CDMAPTALDH1A1LMNAHPGD | |
| SCHEMBL844174 | 0.72 | CNR1 (0.87) | CNR1CNR2PIK3CDKMT2ACREBBP | |
| Hydrochloric Acid SCHEMBL844735 | 0.72 | CNR1 (0.86) | CNR1CNR2PIK3CDKMT2ACREBBP | |
| SCHEMBL844881 | 0.72 | CNR1 (0.69) | CNR1CNR2PIK3CDCREBBP | |
| SCHEMBL11071848 | 0.71 | CNR1 (0.57) | CNR1CNR2PIK3CDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056637-B1 | 4(3H)-QUINAZOLINONE DERIVATIVES, PROCESS FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID COMPOUNDS | Ishikawa, Masayuki (JP) | 1985-07-24 | — | — | EP | claimed |