Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 5/20 | 0.50 |
| ▸ | RARB | P10826 | 4/20 | 0.50 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CHRND | Q07001 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 6/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 3/20 | 0.35 |
| ▸ | RXRB | P28702 | 3/20 | 0.35 |
| ▸ | RXRG | P48443 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CFB | P00751 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976714 | 1.00 | RARG (0.50) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10934691 | 0.87 | RARG (0.43) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10936516 | 0.87 | RARG (0.43) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10936502 | 0.87 | RARG (0.43) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10934712 | 0.87 | RARG (0.43) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10938499 | 0.84 | RARG (0.62) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10938498 | 0.84 | RARG (0.62) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10938507 | 0.84 | RARG (0.62) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10933539 | 0.84 | CA12 (0.41) | RARGRARBCFB | |
| SCHEMBL10933546 | 0.84 | CA12 (0.41) | RARGRARBCFB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155940-A1 | BENZONORBORNENYL, BENZOPYRANYL AND BENZOTHIOPYRANYL RETINOIC ACID ANALOGUES | SRI INTERNATIONAL (US) | 1985-10-02 | — | — | EP | disclosed |
| WO-1985000806-A1 | BENZONORBORNENYL, BENZOPYRANYL AND BENZOTHIOPYRANYL RETINOIC ACID ANALOGUES | SRI INTERNATIONAL (US) | 1985-02-28 | — | — | WO | disclosed |