Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 2/20 | 0.62 |
| ▸ | RARB | P10826 | 1/20 | 0.62 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.47 |
| ▸ | CHRNG | P07510 | 1/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRND | Q07001 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938498 | 1.00 | RARG (0.62) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL10938507 | 1.00 | RARG (0.62) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL10937516 | 0.85 | RARG (0.52) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL10976711 | 0.84 | RARG (0.50) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL10976714 | 0.84 | RARG (0.50) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL1782039 | 0.82 | RARG (0.66) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL1782019 | 0.82 | RARG (0.66) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL1422581 | 0.82 | RARG (0.66) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL10932919 | 0.77 | CHRNB2 (0.73) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL10933004 | 0.77 | RARG (1.00) | RARGRARBCHRNB2CHRNA4CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155940-A1 | BENZONORBORNENYL, BENZOPYRANYL AND BENZOTHIOPYRANYL RETINOIC ACID ANALOGUES | SRI INTERNATIONAL (US) | 1985-10-02 | — | — | EP | disclosed |
| WO-1985000806-A1 | BENZONORBORNENYL, BENZOPYRANYL AND BENZOTHIOPYRANYL RETINOIC ACID ANALOGUES | SRI INTERNATIONAL (US) | 1985-02-28 | — | — | WO | disclosed |