Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | F7 | P08709 | 6/20 | 0.60 |
| ▸ | F3 | P13726 | 6/20 | 0.60 |
| ▸ | PPARG | P37231 | 5/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.60 |
| ▸ | PPARD | Q03181 | 4/20 | 0.60 |
| ▸ | PPARA | Q07869 | 4/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.60 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11296667 | 1.00 | ALDH1A1 (0.60) | ALDH1A1F7F3PPARGFFAR1 | |
| SCHEMBL10976273 | 1.00 | ALDH1A1 (0.60) | ALDH1A1F7F3PPARGFFAR1 | |
| SCHEMBL8740762 | 0.98 | ALDH1A1 (0.62) | ALDH1A1F7F3PPARGFFAR1 | |
| SCHEMBL10483402 | 0.98 | ALDH1A1 (0.62) | ALDH1A1F7F3PPARGFFAR1 | |
| SCHEMBL27513226 | 0.98 | ALDH1A1 (0.62) | ALDH1A1F7F3PPARGFFAR1 | |
| SCHEMBL29769914 | 0.98 | ALDH1A1 (0.62) | ALDH1A1F7F3PPARGFFAR1 | |
| SCHEMBL874446 | 0.95 | ALDH1A1 (0.59) | ALDH1A1F7F3PPARGFFAR1 | |
| SCHEMBL6270744 | 0.95 | ALDH1A1 (0.59) | ALDH1A1F7F3PPARGFFAR1 | |
| SCHEMBL6057135 | 0.95 | ALDH1A1 (0.59) | ALDH1A1F7F3PPARGFFAR1 | |
| SCHEMBL8621450 | 0.95 | ALDH1A1 (0.59) | ALDH1A1F7F3PPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063858-B1 | LEUKOTRIENE ANALOGUES, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | Lilly Industries Limited (GB) | 1985-03-20 | — | — | EP | disclosed |
| EP-0063858-A1 | Leukotriene analogues, their preparation and use in pharmaceutical compositions | Lilly Industries Limited (GB) | 1982-11-03 | — | — | EP | disclosed |