Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 12/20 | 0.68 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | NMBR | P28336 | 1/20 | 0.44 |
| ▸ | IL1RN | P18510 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10979025 | 0.94 | REN (0.76) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10977299 | 0.94 | REN (0.76) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10979028 | 0.94 | REN (0.76) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10721172 | 0.93 | REN (0.65) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10724290 | 0.93 | REN (0.65) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10724591 | 0.93 | REN (0.65) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10725022 | 0.93 | REN (0.65) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10721184 | 0.93 | REN (0.65) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10724177 | 0.93 | REN (0.65) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10725050 | 0.93 | REN (0.65) | RENCTSBCTSKCASP3CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4548926-A | RENIN INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1985-10-22 | — | — | US | disclosed |