Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.63 |
| ▸ | GSK3A | P49840 | 2/20 | 0.63 |
| ▸ | GSK3B | P49841 | 2/20 | 0.63 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.63 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.63 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.63 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.63 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.63 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.63 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976342 | 0.86 | PIM1 (0.63) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL10976310 | 0.85 | PIM1 (0.49) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL10979020 | 0.81 | PIM1 (0.73) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL9615164 | 0.80 | PIM1 (0.72) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL10741051 | 0.78 | PIM1 (0.54) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL10986147 | 0.78 | PIM1 (1.00) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL10976982 | 0.76 | PIM1 (0.79) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL10973484 | 0.75 | PIM1 (0.40) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL10984631 | 0.75 | PIM1 (0.65) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL10976483 | 0.74 | PIM1 (0.73) | PIM1GSK3AGSK3BPIM3PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058392-B1 | SUBSTITUTED CARBOXYLIC ACID DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1985-11-21 | — | — | EP | disclosed |
| US-4426381-A | 1,4-DIHYDROQUINOLIN-4-ONES, FUNGICIDES, BACTERICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1984-01-17 | — | — | US | disclosed |
| EP-0058392-A1 | Substituted carboxylic acid derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1982-08-25 | — | — | EP | disclosed |