SCHEMBL1098043

SCHEMBL1098043

C=C(C)C(=O)Oc1c(F)cc(-c2cc(F)c(OC(=O)C(=C)C)c(F)c2)cc1F

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.38
ALDH1A1 P00352 1/20 0.37
KMT2A Q03164 2/20 0.35
ATM Q13315 1/20 0.35
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
TUBB1 Q9H4B7 2/20 0.33
THRB P10828 1/20 0.32
ERN1 O75460 2/20 0.32
PDGFRB P09619 1/20 0.31
PDGFRA P16234 1/20 0.31
TSHR P16473 1/20 0.31
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3438599 0.89 ERN1 (0.39) ELANEKMT2AATMCYP4F2CYP4A11
SCHEMBL12872190 0.89 ELANE (0.48) ELANEKMT2AATMERN1KIF11
SCHEMBL19157775 0.87 ELANE (0.37) ELANEALDH1A1KMT2AATMCYP4F2
SCHEMBL27710684 0.85 ELANE (0.36) ELANEALDH1A1KMT2AATMCYP4F2
SCHEMBL20672301 0.84 RARB (0.46) ELANE
SCHEMBL15338833 0.83 ERN1 (0.37) ELANEALDH1A1KMT2AATMCYP4F2
SCHEMBL4298943 0.82 ELANE (0.39) ELANEALDH1A1KMT2AATMCYP4F2
SCHEMBL20244886 0.82 FFAR4 (0.36) ELANEALDH1A1TUBB1PDGFRBPDGFRA
SCHEMBL18472699 0.82 DYRK1A (0.37) ELANEKIF11
SCHEMBL803236 0.82 ELANE (0.33) ELANEKMT2AATMCYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153208-B2 Liquid crystal display, a method for manufacturing a liquid crystal display and a liquid crystal composition SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-04-10 US disclosed
US-8153208-B2 Liquid crystal display, a method for manufacturing a liquid crystal display and a liquid crystal composition SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-04-10 US disclosed
US-20100283951-A1 LIQUID CRYSTAL DISPLAY, A METHOD FOR MANUFACTURING A LIQUID CRYSTAL DISPLAY AND A LIQUID CRYSTAL COMPOSITION SAMSUNG DISPLAY CO., LTD. (KR) 2010-11-11 US disclosed
US-20100283951-A1 LIQUID CRYSTAL DISPLAY, A METHOD FOR MANUFACTURING A LIQUID CRYSTAL DISPLAY AND A LIQUID CRYSTAL COMPOSITION SAMSUNG DISPLAY CO., LTD. (KR) 2010-11-11 US disclosed