SCHEMBL3438599

SCHEMBL3438599

C=C(C)C(=O)Oc1ccc(-c2cc(F)c(OC(=O)C(=C)C)c(F)c2)cc1F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.39
CFD P00746 1/20 0.37
ELANE P08246 1/20 0.35
CYP4F2 P78329 1/20 0.35
CYP4A11 Q02928 1/20 0.35
LMNA P02545 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
KIF11 P52732 1/20 0.34
FFAR1 O14842 1/20 0.34
MAPT P10636 1/20 0.33
FFAR4 Q5NUL3 3/20 0.33
AR P10275 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
CYP3A4 P08684 1/20 0.32
AAK1 Q2M2I8 1/20 0.32
JAK2 O60674 1/20 0.32
ABHD6 Q9BV23 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9607788 0.92 CFD (0.42) ERN1CFDELANECYP4F2CYP4A11
SCHEMBL17433322 0.91 CFD (0.41) ERN1CFDELANECYP4F2CYP4A11
SCHEMBL1098043 0.89 ELANE (0.38) ERN1ELANECYP4F2CYP4A11KIF11
SCHEMBL15338833 0.88 ERN1 (0.37) ERN1CFDELANECYP4F2CYP4A11
SCHEMBL2604657 0.88 ERN1 (0.39) ERN1CFDELANELMNAMAPK1
SCHEMBL15385612 0.88 ERN1 (0.40) ERN1CFDELANELMNAMAPK1
SCHEMBL18472702 0.88 CFD (0.50) ERN1CFDELANECYP4F2CYP4A11
SCHEMBL15338908 0.87 ERN1 (0.36) ERN1CFDELANECYP4F2CYP4A11
SCHEMBL24440861 0.87 ELANE (0.40) ERN1CFDELANELMNAMAPK1
SCHEMBL2604650 0.86 ELANE (0.39) ERN1CFDELANELMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2906662-B1 EMITTER AND HOSTS WITH AROMATIC UNITS MERCK PATENT GMBH (DE) 2020-04-01 EP disclosed
US-20160197275-A1 EMITTER HAVING A CONDENSED RING SYSTEM MERCK PATENT GMBH (DE) 2016-07-07 US disclosed
US-20160197275-A1 EMITTER HAVING A CONDENSED RING SYSTEM MERCK PATENT GMBH (DE) 2016-07-07 US disclosed
US-20150340612-A1 UV EMITTERS COMPRISING A MULTIPLE BOND MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-20150340612-A1 UV EMITTERS COMPRISING A MULTIPLE BOND MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-20150270489-A1 EMITTER AND HOSTS WITH AROMATIC UNITS MERCK PATENT GMBH (DE) 2015-09-24 US disclosed
US-20150270489-A1 EMITTER AND HOSTS WITH AROMATIC UNITS MERCK PATENT GMBH (DE) 2015-09-24 US disclosed
WO-2014094965-A2 EMITTER HAVING A CONDENSED RING SYSTEM MERCK PATENT GMBH (DE) 2014-06-26 WO disclosed
US-20120092603-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREFOR SHARP KABUSHIKI KAISHA (JP) 2012-04-19 US disclosed
US-20120092603-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREFOR SHARP KABUSHIKI KAISHA (JP) 2012-04-19 US disclosed