Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 13/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 13/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10983241 | 0.99 | SLC2A1 (0.64) | SLC2A1ADRB2ADRB3ADRB1CYP2D6 | |
| SCHEMBL10938077 | 0.92 | SLC2A1 (0.69) | SLC2A1ADRB2ADRB3ADRB1CYP2D6 | |
| SCHEMBL11152038 | 0.92 | SLC2A1 (0.69) | SLC2A1ADRB2ADRB3ADRB1CYP2D6 | |
| SCHEMBL11161221 | 0.91 | SLC2A1 (0.67) | SLC2A1ADRB2ADRB3ADRB1CYP2D6 | |
| SCHEMBL10899007 | 0.91 | SLC2A1 (0.67) | SLC2A1ADRB2ADRB3ADRB1CYP2D6 | |
| SCHEMBL10936822 | 0.90 | ADRB2 (0.67) | SLC2A1ADRB2ADRB3ADRB1CYP2D6 | |
| Hydrochloric Acid SCHEMBL10896780 | 0.90 | SLC2A1 (0.68) | SLC2A1ADRB2ADRB3ADRB1CYP2D6 | |
| SCHEMBL11035314 | 0.89 | ADRB2 (0.62) | SLC2A1ADRB2ADRB3ADRB1CYP2D6 | |
| SCHEMBL11154189 | 0.89 | ADRB3 (0.74) | SLC2A1ADRB2ADRB3ADRB1CYP2D6 | |
| SCHEMBL10897252 | 0.88 | ADRB2 (0.61) | SLC2A1ADRB2ADRB3ADRB1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066351-B1 | ARYLETHANOL AMINE DERIVATIVES, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1985-06-26 | — | — | EP | claimed |