Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259272 | 0.81 | SLC9A1 (0.53) | CYP2A6ASIC3LOXL2SLC9A1BCL2L1 | |
| SCHEMBL10313792 | 0.71 | BCL2L1 (0.62) | CYP2A6ASIC3LOXL2SLC9A1BCL2L1 | |
| Hydrochloric Acid SCHEMBL4918686 | 0.70 | BCL2L1 (0.61) | CYP2A6ASIC3LOXL2SLC9A1BCL2L1 | |
| SCHEMBL9651173 | 0.70 | SMN1; SMN2 (0.50) | ASIC3LOXL2CA2CA12CA1 | |
| SCHEMBL10929219 | 0.69 | CYP2A6 (0.47) | CYP2A6ASIC3LOXL2SLC9A1BCL2L1 | |
| SCHEMBL2494057 | 0.67 | CYP2A6 (0.44) | CYP2A6ASIC3LOXL2SLC9A1BCL2L1 | |
| SCHEMBL9396821 | 0.67 | CYP2A6 (0.44) | CYP2A6ASIC3LOXL2SLC9A1BCL2L1 | |
| SCHEMBL4912489 | 0.67 | CYP2A6 (0.44) | CYP2A6ASIC3LOXL2SLC9A1BCL2L1 | |
| SCHEMBL10514091 | 0.67 | CYP2A6 (0.53) | CYP2A6ASIC3LOXL2SLC9A1BCL2L1 | |
| SCHEMBL11575531 | 0.67 | BCL2L1 (0.61) | CYP2A6ASIC3LOXL2SLC9A1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4492693-A | BACTERICIDES, ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1985-01-08 | — | — | US | disclosed |