Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994115 | 0.88 | HSD17B10 (0.43) | S1PR1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL11064928 | 0.88 | MAPK1 (0.45) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL10984618 | 0.83 | S1PR1 (0.42) | S1PR1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL10982953 | 0.80 | HTR2A (0.41) | S1PR1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL11042493 | 0.79 | S1PR1 (0.41) | S1PR1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL11065996 | 0.76 | MAPK1 (0.46) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL10986476 | 0.76 | S1PR1 (0.48) | S1PR1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL11064926 | 0.71 | LMNA (0.44) | KMT2AMEN1ALDH1A1MAPTGAA | |
| Hydrochloric Acid SCHEMBL30801151 | 0.69 | MAPT (0.56) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL10987800 | 0.69 | KDM4E (0.41) | KMT2AMEN1ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558043-A | Heterocyclicamino containing benzofurans and 2,3-dihydrobenzofurans, compositions and use | CIBA GEIGY CORPORATION (US) | 1985-12-10 | — | — | US | disclosed |
| US-4451462-A | Method of treating inflammation and pain using heteramino benzofurans | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| US-4426380-A | ANTIINFLAMMATORY, ANALGESIC, SUNSCREEN | CIBA-GEIGY CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |