Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 9/20 | 0.59 |
| ▸ | THRB | P10828 | 9/20 | 0.59 |
| ▸ | RARB | P10826 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | RARA | P10276 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6753083 | 0.85 | THRA (0.58) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9668006 | 0.85 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL12044522 | 0.85 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL19130413 | 0.85 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL195471 | 0.85 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9667265 | 0.85 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9667141 | 0.85 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9667335 | 0.85 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9667123 | 0.85 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL10711276 | 0.84 | THRA (0.56) | THRATHRBRARBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536517-A | ANTIDIABETIC, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | disclosed |