Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11124496 | 1.00 | ALDH1A1 (0.61) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10974774 | 1.00 | ALDH1A1 (0.61) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11128014 | 0.93 | TRPV1 (0.66) | ALDH1A1CYP1A2CYP3A4CYP2D6HPGD | |
| SCHEMBL11127269 | 0.83 | TRPV1 (0.63) | ALDH1A1TRPV1 | |
| SCHEMBL9320943 | 0.80 | S1PR2 (0.50) | — | |
| SCHEMBL15094466 | 0.79 | ALDH1A1 (0.63) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28367131 | 0.78 | ALDH1A1 (0.55) | ALDH1A1CYP3A4 | |
| SCHEMBL11126918 | 0.78 | TRPV1 (0.58) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2800439 | 0.78 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22788513 | 0.78 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068591-B1 | NOVEL SULFONAMIDE DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 1985-09-25 | — | — | EP | disclosed |
| US-4401663-A | ANALGESICS, ANTI-IRRITANTS, DEPILATORIES | THE PROCTER & GAMBLE COMPANY (US) | 1983-08-30 | — | — | US | disclosed |
| EP-0068591-A2 | Novel sulfonamide derivatives | THE PROCTER & GAMBLE COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |