Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | ESR1 | P03372 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.61 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | STS | P08842 | 6/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988890 | 1.00 | ALDH1A1 (0.69) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL28178834 | 1.00 | ALDH1A1 (0.69) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL28408882 | 0.97 | MAPT (0.69) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL10980718 | 0.97 | MAPT (0.69) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL10978226 | 0.97 | MAPT (0.69) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL10395468 | 0.97 | MAPT (0.69) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL10981819 | 0.97 | MAPT (0.69) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL10979708 | 0.97 | MAPT (0.69) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL5709884 | 0.97 | MAPT (0.69) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL17737160 | 0.95 | MAPT (0.64) | ALDH1A1NPC1MAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4507450-A | COORDINATION CATALYSTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1985-03-26 | — | — | US | disclosed |
| US-4229558-A | HAVING HIGH ISOTACTIC INDEX BY USING A CATALYST PREPARED FROM A MAGNESIUM GRIGNARD REAGENT, TITANIUM HALIDE AN ETHER AND A CARBOXYLIC ESTER COMBINED WITH AN ORGANOALUMINUM COMPOUND | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1980-10-21 | — | — | US | disclosed |