Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11124168 | 0.97 | TSHR (0.50) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL10796440 | 0.88 | ALDH1A1 (0.41) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL10595994 | 0.86 | TSHR (0.48) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL10710731 | 0.86 | TSHR (0.65) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL28497716 | 0.84 | TSHR (0.43) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL27797744 | 0.84 | TSHR (0.39) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL10902668 | 0.84 | TSHR (0.52) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| Pentachloronitrobenzene SCHEMBL69247 | 0.83 | TSHR (0.62) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL28759906 | 0.82 | TSHR (0.50) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| Pentachloronitrobenzene SCHEMBL18438924 | 0.80 | TSHR (0.59) | TSHRALDH1A1TDP1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101456928-A | Aromatic organosulfur functionalized 1,4-cis polybutadiene | KUMHO PETROCHEMICAL CO LTD (KR) | 2009-06-17 | — | — | CN | disclosed |
| US-4532350-A | Process for the selective preparation of meta-chloroanilines | RHONE-POULENC AGROCHIMIE (FR) | 1985-07-30 | — | — | US | disclosed |
| US-4418213-A | HYDRODEHALOGENATION LEWIS ACID AND NOBLE METAL CATALYSTS | RHONE-POULENC AGROCHIMIE (FR) | 1983-11-29 | — | — | US | disclosed |
| US-4351959-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-09-28 | — | — | US | disclosed |
| US-4340759-A | Process for the preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-07-20 | — | — | US | disclosed |
| US-4327036-A | FOR AROMATIC NUCLEUS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-04-27 | — | — | US | disclosed |
| US-4324914-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-04-13 | — | — | US | disclosed |