Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.84 |
| ▸ | LMNA | P02545 | 2/20 | 0.84 |
| ▸ | POLB | P06746 | 1/20 | 0.84 |
| ▸ | MAPT | P10636 | 1/20 | 0.84 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | GFER | P55789 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | AKR1C3 | P42330 | 12/20 | 0.71 |
| ▸ | AKR1C2 | P52895 | 12/20 | 0.71 |
| ▸ | CTSV | O60911 | 1/20 | 0.64 |
| ▸ | CTSL | P07711 | 1/20 | 0.64 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31500214 | 1.00 | MEN1 (0.84) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL10834344 | 0.89 | AKR1C3 (0.84) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL11158177 | 0.89 | KMT2A (0.67) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL9593627 | 0.88 | MEN1 (0.83) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL31500229 | 0.86 | AKR1C3 (0.72) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL1415572 | 0.85 | AKR1C3 (0.82) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL9595705 | 0.84 | AKR1C3 (0.71) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL22453057 | 0.83 | MEN1 (0.83) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL31500240 | 0.83 | AKR1C3 (0.69) | MEN1KMT2ALMNAPOLBMAPT | |
| SCHEMBL11426536 | 0.83 | AKR1C3 (0.69) | MEN1KMT2ALMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4549016-A | LIPOXYGENASE INHIBITORS, ANTIALLERGENS, ANTIASTHMA AGENTS | STERLING DRUG INC. (US) | 1985-10-22 | — | — | US | disclosed |
| US-4510139-A | ANTYIALLERGENS; ASTHMA | STERLING DRUG INC. (US) | 1985-04-09 | — | — | US | disclosed |
| US-4496590-A | TREATMENT OR PREVENTION OF ALLERGIC ASTHMA, ANTI-ASTHMATIC | STERLING DRUG INC. (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0122518-A1 | Phenylaminobenzenealkanols and preparation | STERLING DRUG INC. (US) | 1984-10-24 | — | — | EP | disclosed |
| EP-0013144-B1 | SUBSTITUTED DIPHENYLAMINE DERIVATIVES, COMPOSITIONS AND HERBICIDAL USES THEREOF, AND PROCESSES FOR THEIR PREPARATION | ICI AUSTRALIA LIMITED (AU) | 1983-02-23 | — | — | EP | disclosed |
| EP-0013144-A1 | Substituted diphenylamine derivatives, compositions and herbicidal uses thereof, and processes for their preparation | ICI AUSTRALIA LIMITED (AU) | 1980-07-09 | — | — | EP | disclosed |