Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11034035 | 1.00 | TNNC1 (0.53) | TNNC1ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL11034033 | 1.00 | TNNC1 (0.53) | TNNC1ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL10742820 | 1.00 | TNNC1 (0.53) | TNNC1ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL10742834 | 1.00 | TNNC1 (0.53) | TNNC1ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL10742825 | 1.00 | TNNC1 (0.53) | TNNC1ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL10742829 | 1.00 | TNNC1 (0.53) | TNNC1ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL11034034 | 1.00 | TNNC1 (0.53) | TNNC1ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL8837425 | 0.98 | TNNC1 (0.52) | TNNC1ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL23495873 | 0.84 | TNNC1 (0.53) | TNNC1ALDH1A1DUSP3TSHRMAPT | |
| SCHEMBL22438639 | 0.84 | TNNC1 (0.53) | TNNC1ALDH1A1DUSP3TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109225-B1 | ARACHIDONIC ACID ANALOGUES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINE | BEECHAM GROUP PLC (GB) | 1985-08-28 | — | — | EP | claimed |
| EP-0109225-A1 | Arachidonic acid analogues, processes for their preparation and their use in medicine | BEECHAM GROUP PLC (GB) | 1984-05-23 | — | — | EP | claimed |