TNNC1

Troponin C, slow skeletal and cardiac muscles · P63316 · TNNC1 on Sugi Atlas →

20,845 patent compounds predicted against TNNC1, 13,568 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Fingolimod (SCHEMBL7445)	1.00	6/20
Fingolimod (SCHEMBL81362)	0.97	6/20
SCHEMBL565320	0.58	6/20
SCHEMBL775505	0.58	6/20
Hydrochloric Acid (SCHEMBL565883)	0.52	6/20
SCHEMBL140913	0.50	6/20
SCHEMBL566250	0.50	6/20
SCHEMBL566429	0.49	6/20
Hydrochloric Acid (SCHEMBL567052)	0.48	6/20
SCHEMBL566651	0.48	6/20
SCHEMBL86409	0.45	6/20
Hydrochloric Acid (SCHEMBL80436)	0.44	6/20
Hydrochloric Acid (SCHEMBL80437)	0.44	6/20
SCHEMBL86393	0.43	6/20
Hydrochloric Acid (SCHEMBL79318)	0.43	6/20
Hydrochloric Acid (SCHEMBL79319)	0.43	6/20
SCHEMBL86450	0.43	6/20
SCHEMBL86426	0.42	6/20
Hydrochloric Acid (SCHEMBL80616)	0.42	6/20
Hydrochloric Acid (SCHEMBL80617)	0.42	6/20

Clinical trials — most relevant to TNNC1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
The Preventive Efficacy of Carvedilol on Cardiac Dysfunction in Duchenne Muscular Dystrophy	PHASE4	UNKNOWN
Levosimendan in Acute Decompensated Heart Failure	PHASE2/PHASE3	NOT_YET_RECRUITING
Study to Evaluate the Safety, Tolerability, and Immunogenicity of an RNA Vaccine Candidate Against COVID-19 in Healthy Children	PHASE3	COMPLETED
Chronic Sildenafil Treatment in Heart Failure	PHASE3	COMPLETED
Diagnostic and Prognostic Role of Troponin and Brain Natriuretic Peptide in Pediatric Patients With Cardiomyopathy in Correlation to Echocardiography Findings	nan	UNKNOWN
TROPOnin FRAGMentation in Myocardial Injury Study	nan	RECRUITING
The CASABLANCA Study: Catheter Sampled Blood Archive in Cardiovascular Diseases	nan	COMPLETED
A Cardiac Registry to Evaluate and Manage the hsTnI Categorical CVD Risk in Subjects Undergoing Preventive Health Checks (PHC).	nan	SUSPENDED
Cardiac Injury With Convulsive Status Epilepticus	nan	UNKNOWN
Reliability of Cardiac Troponins for the Diagnosis of Myocardial Infarction in the Presence of Skeletal Muscle Disease	nan	ACTIVE_NOT_RECRUITING
Out-of-hospital Cardiac Arrest (OHCA) Biomarkers	nan	COMPLETED
Heart and Skeletal Muscle Problems in Neuroacanthocytosis	nan	COMPLETED
Sleep Disordered Breathing in Acute Congestive Heart Failure	nan	COMPLETED
Rheumatoid Arthritis Disease Activity and Sub Clinical Atherosclerosis	nan	COMPLETED
Observational Study on Cardiac Biomarkers Testing in Patients with Muscular Dystrophy Cardiomyopathy	nan	COMPLETED
Study of Myocardial Function by Speckle Tracking After Cancer Treatment With Anthracyclines in Childhood	nan	COMPLETED
Coronary Angiography in Critically Ill Patients With Type II Myocardial Infarction	nan	WITHDRAWN
Investigation of the Biomarker Copeptin in Patients With Acute Myocardial Infarction	nan	COMPLETED
Finding Acute Coronary Syndromes (ACS) With Serial Troponin Testing for Rapid Assessment of Cardiac Ischemic Symptoms	nan	UNKNOWN
Transcutaneous Functional Magnetic Muscle Stimulation in Critically Ill	nan	UNKNOWN
Improvement of DIAgnostic and Phenotype-genotype Correlation Studies in Patients With MYOpathy Suspected of TITinopathy	nan	UNKNOWN
Early Detection of Cardiomyopathy by Speckle Echo, High Sensitive Troponin and Cardiac Ryanodine Receptors	nan	UNKNOWN
Preoperative BNP: Epidemiological Patterns, Management Strategies and Cost Analysis of Care	nan	COMPLETED
COronary Microcirculation and Troponin Elevation in Septic Shock	nan	COMPLETED
SpinChip Hs-cTnI Determination of the 99th Percentile URL	nan	COMPLETED
Hypersensitive Troponin Performance to Identify Syncope at Risk of Serious Adverse Events in the Short Term	nan	UNKNOWN
Risk Markers in the Acute Coronary Syndromes	nan	COMPLETED
ARgentinean Risk Assessment Registry in ACS; the ARRA-RACS Study	nan	COMPLETED
MACCE in Hospitalized Patients With Community-acquired Pneumonia	nan	UNKNOWN
5th Generation cTnT in ED ACS	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a TNNC1 binder may also engage these)

Protein	Name	Similarity
P02591	—	1.000	P02591 →
P63315	—	1.000	P63315 →
P63317	—	1.000	P63317 →
P09860	—	1.000	P09860 →
P19123	—	1.000	P19123 →
P05936	—	1.000	P05936 →
P02589	—	1.000	P02589 →
P02588	—	1.000	P02588 →
P02585	—	1.000	P02585 →
P10246	—	0.998	P10246 →
P81660	—	0.996	P81660 →
Q3SB11	—	0.995	Q3SB11 →
Q3SB08	—	0.995	Q3SB08 →
Q3SB12	—	0.995	Q3SB12 →
P02587	—	0.994	P02587 →
P20801	—	0.993	P20801 →
P47948	—	0.993	P47948 →
P29291	—	0.993	P29291 →
Q8AY75	—	0.993	Q8AY75 →
Q3SB09	—	0.993	Q3SB09 →
P06708	—	0.993	P06708 →
Q1A7B2	—	0.993	Q1A7B2 →
P02586	—	0.992	P02586 →
P06706	—	0.992	P06706 →
Q1A7B1	—	0.992	Q1A7B1 →
Q09665	—	0.992	Q09665 →
O14008	—	0.992	O14008 →
D2DGW3	—	0.992	D2DGW3 →
P21797	—	0.991	P21797 →
Q3SB14	—	0.991	Q3SB14 →