SCHEMBL10987145

SCHEMBL10987145

C/C=C/C(=O)C1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
TSHR P16473 2/20 0.38
ALDH1A1 P00352 1/20 0.38
RECQL P46063 1/20 0.38
HSD11B1 P28845 3/20 0.34
GAA P10253 1/20 0.34
EPHX1 P07099 1/20 0.33
LMNA P02545 1/20 0.33
SRD5A2 P31213 1/20 0.33
NAAA Q02083 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HTT P42858 1/20 0.32
NPC1 O15118 1/20 0.32
HSD11B2 P80365 1/20 0.32
ACE P12821 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11821390 1.00 CES2 (0.46) CES2CES1HDAC8HDAC6TSHR
SCHEMBL11821386 1.00 CES2 (0.46) CES2CES1HDAC8HDAC6TSHR
SCHEMBL11819065 0.98 CES2 (0.42) CES2CES1HDAC8HDAC6TSHR
SCHEMBL11819068 0.98 CES2 (0.42) CES2CES1HDAC8HDAC6TSHR
SCHEMBL17432039 0.87
SCHEMBL7739531 0.80 CES2 (0.50) CES2CES1HDAC8HDAC6TSHR
SCHEMBL8532638 0.79 CES2 (0.44) CES2CES1HDAC8HDAC6TSHR
SCHEMBL11888155 0.79 ACE (0.35) EPHX1ACE
SCHEMBL8532637 0.79 CES2 (0.44) CES2CES1HDAC8HDAC6TSHR
SCHEMBL7181348 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118126047-A Preparation method of water-based organic negative electrode active material, water-based organic negative electrode and water-based battery 广西电网有限责任公司电力科学研究院 2024-06-04 CN disclosed
US-4492645-A Organoleptic use of cyclohexenyl-alpha-alkyl acrolein derivatives INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-01-08 US disclosed
US-4487701-A ORGANOLEPTIC INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-12-11 US disclosed
US-4480647-A Use of cyclohexenyl-alkyl acrolein derivatives in augmenting or enhancing the aroma or taste of smoking tobacco compositions and smoking tobacco articles INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-11-06 US disclosed
US-4465695-A FLAVOR, AROMA ENHANCERS FOR FOODS, VITAMINS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-08-14 US disclosed
US-4427708-A Use of cyclohexenyl-alpha-alkyl acrolein derivatives in augmenting or enhancing the aroma or taste of foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-01-24 US disclosed
US-4424379-A FLAVORS, TASTES, ODORS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-01-03 US disclosed
US-4416902-A Flavoring with cyclohexenyl-beta-methyl acrolein derivatives INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1983-11-22 US disclosed