SCHEMBL1098744

SCHEMBL1098744

CCCC/C=C(\F)O/C(F)=C/CCCC

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
ALDH1A1 P00352 1/20 0.36
EP300 Q09472 1/20 0.35
GRIK1 P39086 1/20 0.32
LPAR2 Q9HBW0 2/20 0.31
LPAR3 Q9UBY5 2/20 0.31
LPAR1 Q92633 1/20 0.31
F7 P08709 1/20 0.30
F3 P13726 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11497536 0.93 EP300 (0.43) TSHREP300LPAR2LPAR3LPAR1
SCHEMBL25310210 0.85 EP300 (0.42) TSHREP300GRIK1F7F3
SCHEMBL261990 0.84 BACE1 (0.33) TSHRALDH1A1
SCHEMBL27300196 0.77
SCHEMBL7601840 0.77
SCHEMBL3908467 0.76
SCHEMBL27312462 0.74
SCHEMBL262094 0.73
SCHEMBL6911093 0.72 TSHR (0.38) TSHRALDH1A1EP300GRIK1LPAR2
SCHEMBL11752417 0.72 TSHR (0.38) TSHRALDH1A1EP300GRIK1LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153246-B2 Optical compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20090273740-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed
US-20090066898-A1 OPTICALLY-COMPENSATORY SHEET, ELLIPSOIDAL POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-03-12 US disclosed
WO-2007105826-A1 OPTICALLY-COMPENSATORY SHEET, ELLIPSOIDAL POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-09-20 WO disclosed
WO-2007037497-A9 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJI FILM CORP (JP) 2007-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090066898-A1 OPTICALLY-COMPENSATORY SHEET, ELLIPSOIDAL POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE SMN1; SMN2, SPOP, RHOXF2 TSHR 4242/4885ALDH1A1 4417/4885EP300 3759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.